Mistral: Mixtral 8x22B Instruct

mistralai/mixtral-8x22b-instruct

Created Apr 17, 202465,536 context
$0.40/M input tokens$1.20/M output tokens

Mistral's official instruct fine-tuned version of Mixtral 8x22B. It uses 39B active parameters out of 141B, offering unparalleled cost efficiency for its size. Its strengths include:

  • strong math, coding, and reasoning
  • large context length (64k)
  • fluency in English, French, Italian, German, and Spanish

See benchmarks on the launch announcement here. #moe

Sample code and API for Mixtral 8x22B Instruct

OpenRouter normalizes requests and responses across providers for you.

OpenRouter provides an OpenAI-compatible completion API to 300+ models & providers that you can call directly, or using the OpenAI SDK. Additionally, some third-party SDKs are available.

In the examples below, the OpenRouter-specific headers are optional. Setting them allows your app to appear on the OpenRouter leaderboards.

from openai import OpenAI

client = OpenAI(
  base_url="https://openrouter.ai/api/v1",
  api_key="<OPENROUTER_API_KEY>",
)

completion = client.chat.completions.create(
  extra_headers={
    "HTTP-Referer": "<YOUR_SITE_URL>", # Optional. Site URL for rankings on openrouter.ai.
    "X-Title": "<YOUR_SITE_NAME>", # Optional. Site title for rankings on openrouter.ai.
  },
  extra_body={},
  model="mistralai/mixtral-8x22b-instruct",
  messages=[
    {
      "role": "user",
      "content": "What is the meaning of life?"
    }
  ]
)
print(completion.choices[0].message.content)

Using third-party SDKs

For information about using third-party SDKs and frameworks with OpenRouter, please see our frameworks documentation.

See the Request docs for all possible fields, and Parameters for explanations of specific sampling parameters.

More models from Mistral AI

    Mistral: Mixtral 8x22B Instruct – Run with an API | OpenRouter